Exercise training in chronic hypoxia has no effect on ventilatory muscle function in humans.
Détails
ID Serval
serval:BIB_9BDE0A648522
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Exercise training in chronic hypoxia has no effect on ventilatory muscle function in humans.
Périodique
Respiration Physiology
ISSN
0034-5687 (Print)
ISSN-L
0034-5687
Statut éditorial
Publié
Date de publication
1998
Volume
112
Numéro
2
Pages
195-202
Langue
anglais
Résumé
At the highest altitude, aerobic work is limited by environmental oxygen availability. We therefore reasoned that the hyperpnea associated with endurance training at altitude should provide a strong stimulus for adaptation of the ventilatory muscles. We measured peak inspiratory muscle pressure-flow characteristics (inspiring through graded resistors) and maximum sustainable ventilation capacity in ten permanent residents of La Paz, Bolivia (3600 m) prior to and immediately following 6 weeks of incremental endurance training. Additionally, eight local residents did no training and functioned as controls for the capacity test. While V(O2)max measured in hypoxia increased by 19% (Favier et al., 1995b. J. Appl Physiol. 78, 2286-2293.), none of the tested ventilatory variables showed significant changes. The values for the group mean slopes of maximum inspiratory pressure-flow pairs (- 10.5 vs. - 9.8 cm H2O x sec x L(-1), P=0.301; before versus after training, respectively), maximum inspiratory pressure (112.1+/-8.9 vs. 106.9+/-8.6 cmH2O, P=0.163), peak inspiratory flow (9.8+/-0.41 vs. 10.2+/-0.55 L x sec(-1) P=0.172) and the maximum volitional volume in 12 sec (43.9+/-2.4 vs. 45.6+/-2.4 L in 12 sec, P=0.133) were unchanged with exercise training. Likewise, maximal sustainable minute volume was not different between post-training and control subjects (177.4+/-7.9 vs. 165.4+/-8.4 L x min(-1), P=0.141). These data support the concept that endurance training fails to elicit functional adaptations in ventilatory muscles in humans, even when exercise is done in hypoxia.
Mots-clé
Acclimatization, Adaptation, Physiological, Adult, Altitude, Anoxia/physiopathology, Anoxia/therapy, Chronic Disease, Exercise Test, Exercise Therapy, Humans, Lung Volume Measurements, Male, Physical Endurance/physiology, Respiratory Muscles/physiopathology
Pubmed
Web of science
Création de la notice
25/09/2013 13:11
Dernière modification de la notice
20/08/2019 16:02