Thalamic control of cortical states

Détails

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ID Serval
serval:BIB_9AF11C303435
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Production externe
Titre
Thalamic control of cortical states
Périodique
Nature Neuroscience
Auteur⸱e⸱s
Poulet James F A, Fernandez Laura M J, Crochet Sylvain, Petersen Carl C H
ISSN
1097-6256
1546-1726
ISSN-L
1097-6256
Statut éditorial
Publié
Date de publication
22/01/2012
Peer-reviewed
Oui
Volume
15
Numéro
3
Pages
370-372
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: epublish
Résumé
We investigated the impact of thalamus on ongoing cortical activity in the awake, behaving mouse. We demonstrate that the desynchronized cortical state during active behavior is driven by a centrally generated increase in thalamic action potential firing, which can also be mimicked by optogenetic stimulation of the thalamus. The thalamus therefore is key in controlling cortical states.

Mots-clé
Action Potentials/physiology, Afferent Pathways/physiology, Animals, Cortical Synchronization/physiology, Denervation, Electric Stimulation/methods, Fourier Analysis, Mice, Mice, Transgenic, Neurons/physiology, Rhodopsin/genetics, Somatosensory Cortex/cytology, Somatosensory Cortex/physiology, Thalamus/cytology, Thalamus/physiology, Vibrissae/innervation, Wakefulness, General Neuroscience
DOI
10.1038/nn.3035
Pubmed
22267163
Web of science
000300793100009
Création de la notice
09/09/2017 14:42
Dernière modification de la notice
21/08/2019 6:35
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