Tachycardies ventriculaires réfractaires : quelle place pour la radiothérapie et comment ? [Refractory ventricular tachycardia: Is there a role for radiotherapy?]

Détails

ID Serval
serval:BIB_97F278C48DAA
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Tachycardies ventriculaires réfractaires : quelle place pour la radiothérapie et comment ? [Refractory ventricular tachycardia: Is there a role for radiotherapy?]
Périodique
Cancer radiotherapie
Auteur⸱e⸱s
Jumeau R., Pruvot É., Thariat J., Latorzeff I., Milliez P.U., Champ-Rigot L., De Crevoisier R., Ferchaud V.
ISSN
1769-6658 (Electronic)
ISSN-L
1278-3218
Statut éditorial
Publié
Date de publication
10/2020
Peer-reviewed
Oui
Volume
24
Numéro
6-7
Pages
534-546
Langue
français
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Résumé
Myocardial scar-related ventricular tachycardia is a serious and potentially life-threatening arrhythmia. The prevention of sudden rhythmic death and ventricular tachycardia recurrence relies on implantable cardioverter defibrillator (ICD), anti-arrhythmic drugs and more recently on radiofrequency catheter ablation. Nevertheless, these approaches have their own risk of adverse events and complications, with a recurrence rate up to 50 % at 2 years. Stereotactic body radiotherapy, delivered in a single dose of 25Gy, has emerged as a new therapeutic tool in the management of highly refractory ventricular tachycardia. In 2017, the very first prospective 5-patient cohort suffering from recurrent ventricular tachycardia on structural heart disease (40 % of ischemic cardiomyopathy) who benefited from cardiac stereotactic body radiotherapy was published. After stereotactic body radiotherapy, the authors observed a strong ventricular tachycardia burden reduction at 12 months, with no major side effects. Since then, around 100 cases have been described in the literature, particularly in the prospective ENCORE-VT study, with positive short- and medium-term outcomes in terms of safety and ventricular tachycardia burden reduction. Recently, another American prospective 5-patient series, published in March 2020, mitigated these results since all patients presented a ventricular tachycardia recurrence at 12 months despite an initial reduction in ventricular tachycardia burden. This article describes the use of stereotactic body radiotherapy in refractory VT, the rationale of the technique, its implementation, preliminary results and potential acute and long-term consequences.
Mots-clé
Catheter Ablation, Humans, Radiosurgery, Recurrence, Tachycardia, Ventricular/radiotherapy, Tachycardia, Ventricular/surgery, Ablation, Radioablation stéréotaxique, Radiothérapie stéréotaxique, Stereotactic arrhytmia radioablation (STAR), Stereotactic body radiation therapy (SBRT), Tachycardie ventriculaire, Ventricular tachycardia
Pubmed
Web of science
Création de la notice
28/08/2020 7:19
Dernière modification de la notice
04/01/2021 10:54
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