Adeno-associated virus (AAV) as a vector for gene transfer into glial cells of the human central nervous system.

Détails

ID Serval
serval:BIB_96F03E3C4643
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Adeno-associated virus (AAV) as a vector for gene transfer into glial cells of the human central nervous system.
Périodique
Gene Therapy
Auteur⸱e⸱s
Tenenbaum L., Darling J.L., Hooghe-Peters E.
ISSN
0969-7128 (Print)
ISSN-L
0969-7128
Statut éditorial
Publié
Date de publication
1994
Volume
1
Numéro
Suppl 1
Pages
S80
Langue
anglais
Notes
abstract ?
Résumé
To examine the potential of AAV as a vector for gene transfer in glial cells, an established astrocytoma cell line and short-term cultures derived from human oligodendroglioma have been coinfected with AAV and helper adenovirus. The level of AAV replication in glioma cells was high indicating that they express receptors for AAV.
Mots-clé
Astrocytoma/therapy, Astrocytoma/virology, Brain Neoplasms/therapy, Brain Neoplasms/virology, Dependovirus/genetics, Dependovirus/physiology, Gene Therapy, Gene Transfer Techniques, Genetic Vectors, Humans, Oligodendroglioma/therapy, Oligodendroglioma/virology, Tumor Cells, Cultured, Virus Replication
Pubmed
Création de la notice
01/04/2011 10:16
Dernière modification de la notice
20/08/2019 14:58
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