Guidelines on statistics for researchers using laboratory animals: the essentials.

Détails

ID Serval
serval:BIB_94D6593CC4D1
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Guidelines on statistics for researchers using laboratory animals: the essentials.
Périodique
Laboratory animals
Auteur⸱e⸱s
Gosselin R.D.
ISSN
1758-1117 (Electronic)
ISSN-L
0023-6772
Statut éditorial
Publié
Date de publication
02/2019
Peer-reviewed
Oui
Volume
53
Numéro
1
Pages
28-42
Langue
anglais
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Résumé
There is growing concern that the omnipresence of flawed statistics and the deficient reproducibility that arises therefrom results in an unethical waste of animals in research. The present review aims at providing guidelines in biostatistics for researchers, based on observed frequent mistakes, misuses and misconceptions as well as on the specificities of animal experimentation. Twelve recommendations are formulated that cover sampling, sample size optimisation, choice of statistical tests, understanding p-values and reporting results. The objective is to expose important statistical issues that one should consider for the correct design, execution and reporting of experiments.
Mots-clé
Animal Experimentation/statistics & numerical data, Animals, Laboratory Animal Science/methods, Research Design, Sample Size, Statistics as Topic/methods, experimental design, guidelines, reproducibility, sample size, statistics
Pubmed
Web of science
Création de la notice
17/08/2018 16:54
Dernière modification de la notice
02/05/2023 5:55
Données d'usage