Sleep disturbances and incident risk of major depressive disorder in a population-based cohort.
Détails
Etat: Public
Version: Final published version
Licence: CC BY 4.0
ID Serval
serval:BIB_91F484F07506
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Sleep disturbances and incident risk of major depressive disorder in a population-based cohort.
Périodique
Psychiatry research
ISSN
1872-7123 (Electronic)
ISSN-L
0165-1781
Statut éditorial
Publié
Date de publication
08/2024
Peer-reviewed
Oui
Volume
338
Pages
115934
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Résumé
Sleep disturbances are well-known symptoms of major depressive disorder (MDD). However, the prospective risk of MDD in the presence of sleep disturbances in a general population-based cohort is not well known. This study investigated associations between both polysomnography (PSG)-based or subjective sleep features and incident MDD. Participants representative of the general population who had never had MDD completed sleep questionnaires (n = 2000) and/or underwent PSG (n = 717). Over 8 years' follow-up, participants completed psychiatric interviews enabling the diagnosis of MDD. Survival Cox models were used to analyze associations between sleep features and MDD incidence. A higher Epworth Sleepiness Scale and presence of insomnia symptoms were significantly associated with a higher incidence of MDD (hazard ratio [HR] [95 % confidence interval (CI)]: 1.062 [1.022-1.103], p = 0.002 and 1.437 [1.064-1.940], p = 0.018, respectively). Higher density of rapid eye movements in rapid eye movement (REM) sleep was associated with a higher incidence of MDD in men (HR 1.270 [95 % CI 1.064-1.516], p = 0.008). In women, higher delta power spectral density was associated with a lower MDD incidence (HR 0.674 [95 % CI 0.463-0.981], p = 0.039). This study confirmed the associations between subjective and objective sleep features and the incidence of MDD in a large community dwelling cohort.
Mots-clé
Humans, Male, Depressive Disorder, Major/epidemiology, Female, Adult, Middle Aged, Incidence, Sleep Wake Disorders/epidemiology, Polysomnography, Cohort Studies, Sleep Initiation and Maintenance Disorders/epidemiology, Proportional Hazards Models, Surveys and Questionnaires, Risk Factors, Delta power, Depression, Electroencephalogram, Hypersomnia, Insomnia, MDD, Major depressive disorder, REM sleep, Rapid eye movements, Sleep, Sleepiness, Slow wave sleep
Pubmed
Web of science
Open Access
Oui
Création de la notice
14/06/2024 15:56
Dernière modification de la notice
27/07/2024 7:00