Le diabète "MODY". Au delà  de la maladie monogénique ["MODY" diabetes. Beyond a monogenic disease]

Détails

ID Serval
serval:BIB_8EB8F4019664
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Le diabète "MODY". Au delà  de la maladie monogénique ["MODY" diabetes. Beyond a monogenic disease]
Périodique
Schweizerische Rundschau für Medizin Praxis
Auteur(s)
Pinizzotto M., Ruiz J.
ISSN
0369-8394
Statut éditorial
Publié
Date de publication
12/2001
Volume
90
Numéro
51-52
Pages
2255-2260
Notes
21678802 1013-2058 Journal Article --- Old month value: Dec 20 --- Old uritopublisher value: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11820167
Résumé
Maturity Onset Diabetes of the Young is a particular form of type 2 diabetes, classically defined by an autosomal dominant inheritance, a young age at diagnosis (before 25 years) and an insulin secretion defect. At this time, six MODY genes have been described. Beyond the apparent simplicity, the study of such monogenic model of disease may help us to approach a complex disease such as type 2 diabetes, where is involved to conserve a genetic and environmental factors network. This different approach may help us to better understand type 2 diabetes physiopathology.
Mots-clé
Adolescent Adult Child Chromosome Aberrations Diabetes Mellitus, Non-Insulin-Dependent/classification/*genetics/physiopathology English Abstract Female Genes, Dominant Genetic Predisposition to Disease/genetics Genotype Human Male Mutation/genetics Risk Factors Social Environment
Pubmed
Création de la notice
03/03/2008 15:31
Dernière modification de la notice
20/08/2019 14:52
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