Le diabète "MODY". Au delà  de la maladie monogénique ["MODY" diabetes. Beyond a monogenic disease]

Details

Serval ID
serval:BIB_8EB8F4019664
Type
Article: article from journal or magazin.
Collection
Publications
Title
Le diabète "MODY". Au delà  de la maladie monogénique ["MODY" diabetes. Beyond a monogenic disease]
Journal
Schweizerische Rundschau für Medizin Praxis
Author(s)
Pinizzotto M., Ruiz J.
ISSN
0369-8394
Publication state
Published
Issued date
12/2001
Volume
90
Number
51-52
Pages
2255-2260
Notes
21678802 1013-2058 Journal Article --- Old month value: Dec 20 --- Old uritopublisher value: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11820167
Abstract
Maturity Onset Diabetes of the Young is a particular form of type 2 diabetes, classically defined by an autosomal dominant inheritance, a young age at diagnosis (before 25 years) and an insulin secretion defect. At this time, six MODY genes have been described. Beyond the apparent simplicity, the study of such monogenic model of disease may help us to approach a complex disease such as type 2 diabetes, where is involved to conserve a genetic and environmental factors network. This different approach may help us to better understand type 2 diabetes physiopathology.
Keywords
Adolescent Adult Child Chromosome Aberrations Diabetes Mellitus, Non-Insulin-Dependent/classification/*genetics/physiopathology English Abstract Female Genes, Dominant Genetic Predisposition to Disease/genetics Genotype Human Male Mutation/genetics Risk Factors Social Environment
Pubmed
Create date
03/03/2008 15:31
Last modification date
20/08/2019 14:52
Usage data