Trends and determinants of prevalence, awareness, treatment and control of dyslipidaemia in canton of Geneva, 2005-2019: Potent statins are underused.
Détails
Etat: Public
Version: Final published version
Licence: CC BY 4.0
Document(s) secondaire(s)
Télécharger: Supplementary figure 1.pdf (84.80 [Ko])
Etat: Public
Version: Supplementary document
Licence: Non spécifiée
Etat: Public
Version: Supplementary document
Licence: Non spécifiée
Télécharger: Supplementary information.pdf (120.01 [Ko])
Etat: Public
Version: Supplementary document
Licence: Non spécifiée
Etat: Public
Version: Supplementary document
Licence: Non spécifiée
ID Serval
serval:BIB_8B43315C03DA
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Trends and determinants of prevalence, awareness, treatment and control of dyslipidaemia in canton of Geneva, 2005-2019: Potent statins are underused.
Périodique
International journal of cardiology. Cardiovascular risk and prevention
ISSN
2772-4875 (Electronic)
ISSN-L
2772-4875
Statut éditorial
Publié
Date de publication
09/2023
Peer-reviewed
Oui
Volume
18
Pages
200187
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: epublish
Publication Status: epublish
Résumé
We assessed 1) trends in prevalence, awareness, treatment and control rates of dyslipidaemia and associated factors, 2) the effect of statin generation/potency on control levels and 3) the effect of ESC lipid guidelines, on lipid management. Data from multiple cross-sectional, population-based surveys conducted between 2005 and 2019 in the canton of Geneva, Switzerland, were used. Prevalence, awareness, treatment and control rates of dyslipidaemia were 46.0% and 34.9% (p < 0.001), 67.0% and 77.3% (p = 0.124), 40.0% and 19.9% (p < 0.001), and 68.0% and 84.0% (p = 0.255), in 2005 and 2019, respectively. After multivariable adjustment, only the decrease in treatment rates was significant. Increasing age, higher BMI, history of hypertension or diabetes were positively associated with prevalence, while female sex was negatively associated. Female sex, history of diabetes or CVD were positively associated with awareness, while increasing age was negatively associated. Increasing age, smoking, higher BMI, history of hypertension, diabetes or CVD were positively associated with treatment, while female sex was negatively associated. Female sex was positively associated with control, while increasing age was negatively associated. Highly potent statins increased from 50.0% to 87.5% and third generation statins from 0% to 47.5% in 2009 and 2015, respectively. Increased statin potency was borderline (p = 0.059) associated with dyslipidaemia control. ESC guidelines had no effect regarding the prescription of more potent or higher generation statins. We conclude that in the canton of Geneva, treatment of diagnosed dyslipidaemia is low, but control is adequate. Women are undertreated but better controlled than men. The most potent hypolipidemic drugs are underused.
Mots-clé
Control, Dyslipidaemia, Epidemiology, Evolution, Treatment
Pubmed
Web of science
Open Access
Oui
Création de la notice
05/06/2023 9:43
Dernière modification de la notice
27/06/2023 6:54