Long-term sequelae in children surviving adult respiratory distress syndrome.
Détails
ID Serval
serval:BIB_847D5DF02331
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Long-term sequelae in children surviving adult respiratory distress syndrome.
Périodique
Journal of Pediatrics
ISSN
0022-3476
Statut éditorial
Publié
Date de publication
1985
Peer-reviewed
Oui
Volume
106
Numéro
2
Pages
218-222
Langue
anglais
Notes
Publication types: Journal Article
Résumé
Nine children surviving severe adult respiratory distress syndrome were studied 0.9 to 4.2 years after the acute illness. They had received artificial ventilation for a mean of 9.4 days, with an Fio2 greater than 0.5 during a mean time of 34 hours and maximal positive end expiratory pressure levels in the range of 8 to 20 cm H2O. Three children had recurrent respiratory symptoms (moderate exertional dyspnea and cough), and two had evidence of fibrosis on chest radiographs. All patients had abnormal lung function; the most prominent findings were ventilation inequalities, as judged by real-time moment ratio analysis of multibreath nitrogen washout curves (abnormal in eight of nine patients) and hypoxemia (seven of nine). Lung volumes were less abnormal; one patient had restrictive and two had obstructive disease. A significant correlation between intensive care measures (Fio2 greater than 0.5 in hours and peak inspiratory plateau pressure) and lung function abnormalities (moment ratio analysis and hypoxemia) was found. A possibly increased susceptibility of the pediatric age group to the primary insult or respiratory therapy of adult respiratory distress syndrome is suggested.
Mots-clé
Adolescent, Child, Child, Preschool, Echocardiography, Electrocardiography, Emergencies, Follow-Up Studies, Heart, Humans, Lung, Lung Volume Measurements, Physical Examination, Positive-Pressure Respiration, Respiration, Artificial, Respiratory Distress Syndrome, Adult, Respiratory Function Tests
Pubmed
Web of science
Création de la notice
25/01/2008 11:07
Dernière modification de la notice
20/08/2019 15:44