Long-term sequelae in children surviving adult respiratory distress syndrome.

Details

Serval ID
serval:BIB_847D5DF02331
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Long-term sequelae in children surviving adult respiratory distress syndrome.
Journal
Journal of Pediatrics
Author(s)
Fanconi S., Kraemer R., Weber J., Tschaeppeler H., Pfenninger J.
ISSN
0022-3476
Publication state
Published
Issued date
1985
Peer-reviewed
Oui
Volume
106
Number
2
Pages
218-222
Language
english
Notes
Publication types: Journal Article
Abstract
Nine children surviving severe adult respiratory distress syndrome were studied 0.9 to 4.2 years after the acute illness. They had received artificial ventilation for a mean of 9.4 days, with an Fio2 greater than 0.5 during a mean time of 34 hours and maximal positive end expiratory pressure levels in the range of 8 to 20 cm H2O. Three children had recurrent respiratory symptoms (moderate exertional dyspnea and cough), and two had evidence of fibrosis on chest radiographs. All patients had abnormal lung function; the most prominent findings were ventilation inequalities, as judged by real-time moment ratio analysis of multibreath nitrogen washout curves (abnormal in eight of nine patients) and hypoxemia (seven of nine). Lung volumes were less abnormal; one patient had restrictive and two had obstructive disease. A significant correlation between intensive care measures (Fio2 greater than 0.5 in hours and peak inspiratory plateau pressure) and lung function abnormalities (moment ratio analysis and hypoxemia) was found. A possibly increased susceptibility of the pediatric age group to the primary insult or respiratory therapy of adult respiratory distress syndrome is suggested.
Keywords
Adolescent, Child, Child, Preschool, Echocardiography, Electrocardiography, Emergencies, Follow-Up Studies, Heart, Humans, Lung, Lung Volume Measurements, Physical Examination, Positive-Pressure Respiration, Respiration, Artificial, Respiratory Distress Syndrome, Adult, Respiratory Function Tests
Pubmed
Web of science
Create date
25/01/2008 10:07
Last modification date
20/08/2019 14:44
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