Focus on stereotactic radiotherapy: A new way to treat severe ventricular arrhythmias?

Détails

ID Serval
serval:BIB_82755970F3AF
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Focus on stereotactic radiotherapy: A new way to treat severe ventricular arrhythmias?
Périodique
Archives of cardiovascular diseases
Auteur⸱e⸱s
Sacher F., Gandjbakhch E., Maury P., Jenny C., Khalifa J., Boveda S., Defaye P., Gras D., Klug D., Laurent G., Lellouche N., Mansourati J., Marijon E., Piot O., Taieb J., Cochet H., Maingon P., Pruvot E., Fauchier L.
Collaborateur⸱rice⸱s
Working Group of Cardiac Pacing, Electrophysiology of the French Society of Cardiology
ISSN
1875-2128 (Electronic)
ISSN-L
1875-2128
Statut éditorial
Publié
Date de publication
02/2021
Peer-reviewed
Oui
Volume
114
Numéro
2
Pages
140-149
Langue
anglais
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Résumé
Ventricular tachycardia has a significant recurrence rate after ablation for several reasons, including inaccessible substrate. A non-invasive technique to ablate any defined areas of myocardium involved in arrhythmogenesis would be a potentially important therapeutic improvement if shown to be safe and effective. Early feasibility studies of single-fraction stereotactic body radiotherapy have demonstrated encouraging results, but rigorous evaluation and follow-up are required. In this document, the basic concepts of stereotactic body radiotherapy are summarized, before focusing on stereotactic arrhythmia radioablation. We describe the effect of radioablation on cardiac tissue and its interaction with intracardiac devices, depending on the dose. The different clinical studies on ventricular tachycardia radioablation are analysed, with a focus on target identification, which is the key feature of this approach. Our document ends with the indications and requirements for practicing this type of procedure in 2020. Finally, because of the limited number of patients treated so far, we encourage multicentre registries with long-term follow-up.
Mots-clé
Action Potentials, Aged, Aged, 80 and over, Animals, Female, Heart Rate, Heart Ventricles/physiopathology, Heart Ventricles/radiation effects, Humans, Male, Middle Aged, Radiosurgery/adverse effects, Risk Factors, Tachycardia, Ventricular/diagnosis, Tachycardia, Ventricular/physiopathology, Tachycardia, Ventricular/radiotherapy, Treatment Outcome, Ablation, Catheter ablation, Radiothérapie stéréotaxique, Stereotactic body radiation therapy, Stereotactic radiotherapy, Tachycardie ventriculaire, Ventricular tachycardia
Pubmed
Web of science
Création de la notice
08/02/2021 10:03
Dernière modification de la notice
17/04/2021 6:33
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