Massive cerebral edema after I.V. cyclosporin overdose.
Détails
ID Serval
serval:BIB_809947DC9CA8
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Institution
Titre
Massive cerebral edema after I.V. cyclosporin overdose.
Périodique
Transplantation
ISSN
0041-1337[print], 0041-1337[linking]
Statut éditorial
Publié
Date de publication
2000
Volume
70
Numéro
8
Pages
1259-1260
Langue
anglais
Notes
Publication types: Case Reports ; Journal Article
Résumé
We describe a patient who accidentally received an infusion of cyclosporin at a rate of 30 mg/hr during 13 hr instead of the prescribed dose of 3 mg/hr and who concomitantly developed massive intracerebral edema with brainstem compression and death. A cyclosporin level as high as 1700 ng/ml could have been reached before the drug was withdrawn. To the best of our knowledge, this is the first case of fatal cyclosporin overdose reported in an adult patient.
Mots-clé
Brain Edema/chemically induced, Cyclosporine/administration & dosage, Cyclosporine/adverse effects, Humans, Injections, Intravenous, Male, Middle Aged, Overdose/etiology
Pubmed
Web of science
Création de la notice
19/02/2010 19:56
Dernière modification de la notice
20/08/2019 15:41