Article: article from journal or magazin.
Case report (case report): feedback on an observation with a short commentary.
Massive cerebral edema after I.V. cyclosporin overdose.
Publication types: Case Reports ; Journal Article
We describe a patient who accidentally received an infusion of cyclosporin at a rate of 30 mg/hr during 13 hr instead of the prescribed dose of 3 mg/hr and who concomitantly developed massive intracerebral edema with brainstem compression and death. A cyclosporin level as high as 1700 ng/ml could have been reached before the drug was withdrawn. To the best of our knowledge, this is the first case of fatal cyclosporin overdose reported in an adult patient.
Brain Edema/chemically induced, Cyclosporine/administration & dosage, Cyclosporine/adverse effects, Humans, Injections, Intravenous, Male, Middle Aged, Overdose/etiology
Web of science
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