Treating high blood pressure: is reaching the target more important than the means? No, the means are important.

Détails

ID Serval
serval:BIB_7A595F4BCA2B
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Treating high blood pressure: is reaching the target more important than the means? No, the means are important.
Périodique
European Journal of Internal Medicine
Auteur⸱e⸱s
Forni V., Wuerzner G., Pruijm M., Burnier M.
ISSN
1879-0828 (Electronic)
ISSN-L
0953-6205
Statut éditorial
Publié
Date de publication
2010
Volume
21
Numéro
6
Pages
478-483
Langue
anglais
Notes
Publication types: Journal ArticlePublication Status: ppublish. pdf type: debate
Résumé
All major antihypertensive drug classes i.e. diuretics, beta-blockers, calcium antagonists and blockers of the renin-angiotensin system have been shown to effectively lower blood pressure and hence to reduce cardiovascular outcomes in hypertensive patients. These drugs decrease cardiovascular complications in hypertension essentially because they reduce systemic blood pressure. Nevertheless, there is growing evidence that the extent of the benefits differed between drug classes suggesting that the various classes of antihypertensive agents are not equivalent in their ability to protect against target organ damages and cardiovascular and renal endpoints. More recently, evidence has also accumulated to demonstrate that even combination therapies are not equally effective in reducing the occurrence of cardiovascular complications in hypertension. These recent observations suggest that the means to lower blood pressure are as important as the achieved target blood pressure in the management of hypertensive patients.
Mots-clé
Antihypertensive Agents/therapeutic use, Blood Pressure/drug effects, Comorbidity, Heart Diseases/epidemiology, Heart Diseases/prevention & control, Humans, Hypertension, Renal/drug therapy, Hypertension, Renal/epidemiology, Stroke/epidemiology, Stroke/prevention & control
Pubmed
Web of science
Création de la notice
13/03/2013 15:35
Dernière modification de la notice
20/08/2019 14:36
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