Treating high blood pressure: is reaching the target more important than the means? No, the means are important.

Details

Serval ID
serval:BIB_7A595F4BCA2B
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Treating high blood pressure: is reaching the target more important than the means? No, the means are important.
Journal
European Journal of Internal Medicine
Author(s)
Forni V., Wuerzner G., Pruijm M., Burnier M.
ISSN
1879-0828 (Electronic)
ISSN-L
0953-6205
Publication state
Published
Issued date
2010
Volume
21
Number
6
Pages
478-483
Language
english
Notes
Publication types: Journal ArticlePublication Status: ppublish. pdf type: debate
Abstract
All major antihypertensive drug classes i.e. diuretics, beta-blockers, calcium antagonists and blockers of the renin-angiotensin system have been shown to effectively lower blood pressure and hence to reduce cardiovascular outcomes in hypertensive patients. These drugs decrease cardiovascular complications in hypertension essentially because they reduce systemic blood pressure. Nevertheless, there is growing evidence that the extent of the benefits differed between drug classes suggesting that the various classes of antihypertensive agents are not equivalent in their ability to protect against target organ damages and cardiovascular and renal endpoints. More recently, evidence has also accumulated to demonstrate that even combination therapies are not equally effective in reducing the occurrence of cardiovascular complications in hypertension. These recent observations suggest that the means to lower blood pressure are as important as the achieved target blood pressure in the management of hypertensive patients.
Keywords
Antihypertensive Agents/therapeutic use, Blood Pressure/drug effects, Comorbidity, Heart Diseases/epidemiology, Heart Diseases/prevention & control, Humans, Hypertension, Renal/drug therapy, Hypertension, Renal/epidemiology, Stroke/epidemiology, Stroke/prevention & control
Pubmed
Web of science
Create date
13/03/2013 16:35
Last modification date
20/08/2019 15:36
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