Prevalence Estimate of Blood Doping in Elite Track and Field Athletes During Two Major International Events.

Détails

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Etat: Public
Version: Final published version
Licence: CC BY 4.0
ID Serval
serval:BIB_78FC8C51BAC6
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Prevalence Estimate of Blood Doping in Elite Track and Field Athletes During Two Major International Events.
Périodique
Frontiers in physiology
Auteur⸱e⸱s
Faiss R., Saugy J., Zollinger A., Robinson N., Schuetz F., Saugy M., Garnier PY
ISSN
1664-042X (Print)
ISSN-L
1664-042X
Statut éditorial
Publié
Date de publication
25/02/2020
Peer-reviewed
Oui
Volume
11
Pages
160
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: epublish
Résumé
In elite sport, the Athlete Biological Passport (ABP) was invented to tackle cheaters by monitoring closely changes in biological parameters, flagging atypical variations. The hematological module of the ABP was indeed adopted in 2011 by World Athletics (WA). This study estimates the prevalence of blood doping based on hematological parameters in a large cohort of track and field athletes measured at two international major events (2011 and 2013 WA World Championships) with a hypothesized decrease in prevalence due to the ABP introduction. A total of 3683 blood samples were collected and analyzed from all participating athletes originating from 209 countries. The estimate of doping prevalence was obtained by using a Bayesian network with seven variables, as well as "blood doping" as a variable mimicking doping with low-doses of recombinant human erythropoietin (rhEPO), to generate reference cumulative distribution functions (CDFs) for the Abnormal Blood Profile Score (ABPS) from the ABP. Our results from robust hematological parameters indicate an estimation of an overall blood doping prevalence of 18% in 2011 and 15% in 2013 (non-significant difference) in average in endurance athletes [95% Confidence Interval (CI) 14-22 and 12-19% for 2011 and 2013, respectively]. A higher prevalence was observed in female athletes (22%, CI 16-28%) than in male athletes (15%, CI 9-20%) in 2011. In conclusion, this study presents the first comparison of blood doping prevalence in elite athletes based on biological measurements from major international events that may help scientists and experts to use the ABP in a more efficient and deterrent way.
Mots-clé
athletes, blood, doping, hematological passport, prevalence
Pubmed
Web of science
Open Access
Oui
Création de la notice
23/03/2020 8:25
Dernière modification de la notice
30/11/2023 17:49
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