Prevalence Estimate of Blood Doping in Elite Track and Field Athletes During Two Major International Events.

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State: Public
Version: Final published version
License: CC BY 4.0
Serval ID
serval:BIB_78FC8C51BAC6
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Prevalence Estimate of Blood Doping in Elite Track and Field Athletes During Two Major International Events.
Journal
Frontiers in physiology
Author(s)
Faiss R., Saugy J., Zollinger A., Robinson N., Schuetz F., Saugy M., Garnier PY
ISSN
1664-042X (Print)
ISSN-L
1664-042X
Publication state
Published
Issued date
25/02/2020
Peer-reviewed
Oui
Volume
11
Pages
160
Language
english
Notes
Publication types: Journal Article
Publication Status: epublish
Abstract
In elite sport, the Athlete Biological Passport (ABP) was invented to tackle cheaters by monitoring closely changes in biological parameters, flagging atypical variations. The hematological module of the ABP was indeed adopted in 2011 by World Athletics (WA). This study estimates the prevalence of blood doping based on hematological parameters in a large cohort of track and field athletes measured at two international major events (2011 and 2013 WA World Championships) with a hypothesized decrease in prevalence due to the ABP introduction. A total of 3683 blood samples were collected and analyzed from all participating athletes originating from 209 countries. The estimate of doping prevalence was obtained by using a Bayesian network with seven variables, as well as "blood doping" as a variable mimicking doping with low-doses of recombinant human erythropoietin (rhEPO), to generate reference cumulative distribution functions (CDFs) for the Abnormal Blood Profile Score (ABPS) from the ABP. Our results from robust hematological parameters indicate an estimation of an overall blood doping prevalence of 18% in 2011 and 15% in 2013 (non-significant difference) in average in endurance athletes [95% Confidence Interval (CI) 14-22 and 12-19% for 2011 and 2013, respectively]. A higher prevalence was observed in female athletes (22%, CI 16-28%) than in male athletes (15%, CI 9-20%) in 2011. In conclusion, this study presents the first comparison of blood doping prevalence in elite athletes based on biological measurements from major international events that may help scientists and experts to use the ABP in a more efficient and deterrent way.
Keywords
athletes, blood, doping, hematological passport, prevalence
Pubmed
Web of science
Open Access
Yes
Create date
23/03/2020 8:25
Last modification date
02/03/2021 6:25
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