Laminar specificity of intrinsic connections in Broca's area.
Détails
Etat: Public
Version: Final published version
Licence: Non spécifiée
It was possible to publish this article open access thanks to a Swiss National Licence with the publisher.
ID Serval
serval:BIB_72A5F5754BED
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Laminar specificity of intrinsic connections in Broca's area.
Périodique
Cerebral Cortex
ISSN
1460-2199[electronic]
Statut éditorial
Publié
Date de publication
2007
Volume
17
Numéro
12
Pages
2949-2960
Langue
anglais
Notes
Journal article --- Old month value: Mar 29
Résumé
Broca's area and its right hemisphere homologue comprise 2 cytoarchitectonic subdivisions, FDgamma and FCBm of von Economo C and Koskinas GN (1925, Die Cytoarchitektonik der Hirnrinde des erwachsenen Menschen. Vienna/Berlin [Germany]: Springer). We report here on intrinsic connections within these areas, as revealed with biotinylated dextran amine and 1,1'-dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine perchlorate tracing in postmortem human brains. Injections limited to supragranular layers revealed a complex intrinsic network of horizontal connections within layers II and III spreading over several millimeters and to a lesser extent within layers IV, V, and VI. Ninety percent of the retrogradely labeled neurons (n = 734) were in supragranular layers, 4% in layer IV, and 6% in infragranular layers; most were pyramids and tended to be grouped into clusters of approximately 500 microm in diameter. Injections involving layer IV revealed extended horizontal connections within layers I-IV (up to 3.7 mm) and to a lesser extent in layers V and VI. Injections limited to the infragranular layers revealed horizontal connections mainly limited to these layers. Thus, intrinsic connections within Broca's area display a strong laminar specificity. This pattern is very similar in areas FDgamma and FCBm and in the 2 hemispheres.
Mots-clé
Aged, Aged, 80 and over, Female, Frontal Lobe, Humans, Male, Nerve Net, Neural Pathways
Pubmed
Web of science
Open Access
Oui
Création de la notice
25/01/2008 12:34
Dernière modification de la notice
14/02/2022 8:55