Semantic memory assessment in 15 patients with amyotrophic lateral sclerosis.
Détails
Etat: Public
Version: Final published version
Licence: Non spécifiée
ID Serval
serval:BIB_6FA052D19029
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Semantic memory assessment in 15 patients with amyotrophic lateral sclerosis.
Périodique
Revue neurologique
ISSN
0035-3787 (Print)
ISSN-L
0035-3787
Statut éditorial
Publié
Date de publication
2016
Peer-reviewed
Oui
Volume
172
Numéro
4-5
Pages
307-312
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Résumé
A total of 30 to 50% of amyotrophic lateral sclerosis patients suffer from cognitive disorders. The aim of the study is to characterize these disorders and to assess semantic memory in non-demented ALS patients. The secondary aim is to look for a link between disease type and neuropsychological characteristics.
Patients were followed in an ALS center in Dijon. The following neuropsychological tests were used in this study: Folstein test, BREF test, verbal fluency, Isaac test, GRESEM test and TOP 30 test.
Fifteen ALS patients were included. Nine of them (60%) were suffering from a semantic memory disorder. There was no correlation between ALS characteristics and the semantic memory disorder.
This is the first study to reveal a semantic memory disorder in ALS. This result accentuates the hypothesis that ALS and semantic dementia are two phenotypes of the same degenerative process linked to TDP 43 proteinopathy.
Patients were followed in an ALS center in Dijon. The following neuropsychological tests were used in this study: Folstein test, BREF test, verbal fluency, Isaac test, GRESEM test and TOP 30 test.
Fifteen ALS patients were included. Nine of them (60%) were suffering from a semantic memory disorder. There was no correlation between ALS characteristics and the semantic memory disorder.
This is the first study to reveal a semantic memory disorder in ALS. This result accentuates the hypothesis that ALS and semantic dementia are two phenotypes of the same degenerative process linked to TDP 43 proteinopathy.
Mots-clé
Adult, Aged, Aged, 80 and over, Amyotrophic Lateral Sclerosis/complications, Amyotrophic Lateral Sclerosis/diagnosis, Amyotrophic Lateral Sclerosis/psychology, Cohort Studies, Female, Humans, Male, Memory, Memory Disorders/diagnosis, Memory Disorders/etiology, Middle Aged, Neuropsychological Tests, Semantics, Severity of Illness Index, Amyotrophic lateral sclerosis, Semantic memory
Pubmed
Web of science
Création de la notice
23/08/2024 8:59
Dernière modification de la notice
23/08/2024 9:34
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