Semantic memory assessment in 15 patients with amyotrophic lateral sclerosis.
Details
State: Public
Version: Final published version
License: Not specified
Serval ID
serval:BIB_6FA052D19029
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Semantic memory assessment in 15 patients with amyotrophic lateral sclerosis.
Journal
Revue neurologique
ISSN
0035-3787 (Print)
ISSN-L
0035-3787
Publication state
Published
Issued date
2016
Peer-reviewed
Oui
Volume
172
Number
4-5
Pages
307-312
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Abstract
A total of 30 to 50% of amyotrophic lateral sclerosis patients suffer from cognitive disorders. The aim of the study is to characterize these disorders and to assess semantic memory in non-demented ALS patients. The secondary aim is to look for a link between disease type and neuropsychological characteristics.
Patients were followed in an ALS center in Dijon. The following neuropsychological tests were used in this study: Folstein test, BREF test, verbal fluency, Isaac test, GRESEM test and TOP 30 test.
Fifteen ALS patients were included. Nine of them (60%) were suffering from a semantic memory disorder. There was no correlation between ALS characteristics and the semantic memory disorder.
This is the first study to reveal a semantic memory disorder in ALS. This result accentuates the hypothesis that ALS and semantic dementia are two phenotypes of the same degenerative process linked to TDP 43 proteinopathy.
Patients were followed in an ALS center in Dijon. The following neuropsychological tests were used in this study: Folstein test, BREF test, verbal fluency, Isaac test, GRESEM test and TOP 30 test.
Fifteen ALS patients were included. Nine of them (60%) were suffering from a semantic memory disorder. There was no correlation between ALS characteristics and the semantic memory disorder.
This is the first study to reveal a semantic memory disorder in ALS. This result accentuates the hypothesis that ALS and semantic dementia are two phenotypes of the same degenerative process linked to TDP 43 proteinopathy.
Keywords
Adult, Aged, Aged, 80 and over, Amyotrophic Lateral Sclerosis/complications, Amyotrophic Lateral Sclerosis/diagnosis, Amyotrophic Lateral Sclerosis/psychology, Cohort Studies, Female, Humans, Male, Memory, Memory Disorders/diagnosis, Memory Disorders/etiology, Middle Aged, Neuropsychological Tests, Semantics, Severity of Illness Index, Amyotrophic lateral sclerosis, Semantic memory
Pubmed
Web of science
Create date
23/08/2024 9:59
Last modification date
23/08/2024 10:34
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