Wound repair and regeneration.

Détails

ID Serval
serval:BIB_6B7F2E366441
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Wound repair and regeneration.
Périodique
Nature
Auteur⸱e⸱s
Gurtner G.C., Werner S., Barrandon Y., Longaker M.T.
ISSN
1476-4687
Statut éditorial
Publié
Date de publication
2008
Peer-reviewed
Oui
Volume
453
Numéro
7193
Pages
314-321
Langue
anglais
Résumé
The repair of wounds is one of the most complex biological processes that occur during human life. After an injury, multiple biological pathways immediately become activated and are synchronized to respond. In human adults, the wound repair process commonly leads to a non-functioning mass of fibrotic tissue known as a scar. By contrast, early in gestation, injured fetal tissues can be completely recreated, without fibrosis, in a process resembling regeneration. Some organisms, however, retain the ability to regenerate tissue throughout adult life. Knowledge gained from studying such organisms might help to unlock latent regenerative pathways in humans, which would change medical practice as much as the introduction of antibiotics did in the twentieth century.
Mots-clé
Animals, Fibrosis, Humans, Intercellular Signaling Peptides and Proteins, Regeneration, Regenerative Medicine, Stem Cells, Wound Healing
Pubmed
Web of science
Création de la notice
25/02/2009 10:45
Dernière modification de la notice
20/08/2019 15:25
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