Cytotoxic coumarins from the aerial parts of Tordylium apulum and their effects on a non-small-cell bronchial carcinoma line
Détails
ID Serval
serval:BIB_688D4C285B1D
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Lettre (letter): communication adressée à l'éditeur.
Collection
Publications
Institution
Titre
Cytotoxic coumarins from the aerial parts of Tordylium apulum and their effects on a non-small-cell bronchial carcinoma line
Périodique
Planta Medica
ISSN
0032-0943 (Print)
Statut éditorial
Publié
Date de publication
03/1998
Volume
64
Numéro
2
Pages
174-6
Notes
Letter
Research Support, Non-U.S. Gov't --- Old month value: Mar
Research Support, Non-U.S. Gov't --- Old month value: Mar
Résumé
Seven coumarins were isolated from the aerial parts of Tordylium apulum; their structures were established by spectroscopic means. All compounds were tested in vitro for their cytotoxicity against two cell line systems. The antiproliferative effects for three of them were studied at the level of the cell cycle in asynchronous cells of the NSCLC-N6 line with a flow cytometry apparatus.
Mots-clé
Angiosperms
Antineoplastic Agents, Phytogenic/chemistry/*isolation &
purification/toxicity
Carcinoma, Non-Small-Cell Lung
Cell Survival/drug effects
Coumarins/chemistry/*isolation & purification/toxicity
Humans
KB Cells
Lung Neoplasms
*Plants, Medicinal
Tumor Cells, Cultured
Pubmed
Web of science
Création de la notice
25/01/2008 13:59
Dernière modification de la notice
20/08/2019 15:23
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