Cytotoxic coumarins from the aerial parts of Tordylium apulum and their effects on a non-small-cell bronchial carcinoma line

Details

Serval ID
serval:BIB_688D4C285B1D
Type
Article: article from journal or magazin.
Publication sub-type
Letter (letter): Communication to the publisher.
Collection
Publications
Institution
Title
Cytotoxic coumarins from the aerial parts of Tordylium apulum and their effects on a non-small-cell bronchial carcinoma line
Journal
Planta Medica
Author(s)
Kofinas  C., Chinou  I., Loukis  A., Harvala  C., Roussakis  C., Maillard  M., Hostettmann  K.
ISSN
0032-0943 (Print)
Publication state
Published
Issued date
03/1998
Volume
64
Number
2
Pages
174-6
Notes
Letter
Research Support, Non-U.S. Gov't --- Old month value: Mar
Abstract
Seven coumarins were isolated from the aerial parts of Tordylium apulum; their structures were established by spectroscopic means. All compounds were tested in vitro for their cytotoxicity against two cell line systems. The antiproliferative effects for three of them were studied at the level of the cell cycle in asynchronous cells of the NSCLC-N6 line with a flow cytometry apparatus.
Keywords
Angiosperms Antineoplastic Agents, Phytogenic/chemistry/*isolation & purification/toxicity Carcinoma, Non-Small-Cell Lung Cell Survival/drug effects Coumarins/chemistry/*isolation & purification/toxicity Humans KB Cells Lung Neoplasms *Plants, Medicinal Tumor Cells, Cultured
Pubmed
Web of science
Create date
25/01/2008 12:59
Last modification date
20/08/2019 14:23
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