Combined Lung and Liver Transplantation for Short Telomere Syndrome.
Détails
Télécharger: 32080954_pp_cover.pdf (3780.76 [Ko])
Etat: Public
Version: Author's accepted manuscript
Licence: Tous droits réservés
Etat: Public
Version: Author's accepted manuscript
Licence: Tous droits réservés
ID Serval
serval:BIB_67847DD9BC0A
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Institution
Titre
Combined Lung and Liver Transplantation for Short Telomere Syndrome.
Périodique
Liver transplantation
ISSN
1527-6473 (Electronic)
ISSN-L
1527-6465
Statut éditorial
Publié
Date de publication
06/2020
Peer-reviewed
Oui
Volume
26
Numéro
6
Pages
840-844
Langue
anglais
Notes
Publication types: Letter
Publication Status: ppublish
PDF: Letter to the editor
Publication Status: ppublish
PDF: Letter to the editor
Résumé
Telomeres are DNA-protein structures located at the chromosome ends and terminating with an essential single-stranded 3'-overhang. <sup>1</sup> Their role is to maintain genomic integrity by protecting chromosomes from degradation and illegitimate recombination. Telomeres progressively shorten during cell division because of the inability of DNA polymerase to replicate the 3'-end of chromosomes. Telomerase limits telomere attrition by synthesizing de novo telomere sequences at the end of chromosomes.
Pubmed
Web of science
Création de la notice
27/02/2020 15:50
Dernière modification de la notice
21/11/2022 8:26