Combined Lung and Liver Transplantation for Short Telomere Syndrome.

Details

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State: Public
Version: Author's accepted manuscript
License: All rights reserved
Serval ID
serval:BIB_67847DD9BC0A
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Combined Lung and Liver Transplantation for Short Telomere Syndrome.
Journal
Liver transplantation
Author(s)
Moschouri E., Vionnet J., Giostra E., Daccord C., Lazor R., Sciarra A., Letovanec I., Sempoux C., Gonzalez M., Unger S., Fodstad H., Haubitz M., Baerlocher G.M., Voruz S., Naveiras O., Jacquemin E., Moradpour D., Fraga M.
ISSN
1527-6473 (Electronic)
ISSN-L
1527-6465
Publication state
Published
Issued date
06/2020
Peer-reviewed
Oui
Volume
26
Number
6
Pages
840-844
Language
english
Notes
Publication types: Letter
Publication Status: ppublish
PDF: Letter to the editor
Abstract
Telomeres are DNA-protein structures located at the chromosome ends and terminating with an essential single-stranded 3'-overhang. <sup>1</sup> Their role is to maintain genomic integrity by protecting chromosomes from degradation and illegitimate recombination. Telomeres progressively shorten during cell division because of the inability of DNA polymerase to replicate the 3'-end of chromosomes. Telomerase limits telomere attrition by synthesizing de novo telomere sequences at the end of chromosomes.
Pubmed
Web of science
Create date
27/02/2020 16:50
Last modification date
11/05/2021 6:34
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