Going with the membrane flow: the impact of polarized secretion on bulk plasma membrane flows.

Détails

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Accès restreint UNIL
Etat: Public
Version: Author's accepted manuscript
Licence: CC BY 4.0
ID Serval
serval:BIB_6391CD6FACE0
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Going with the membrane flow: the impact of polarized secretion on bulk plasma membrane flows.
Périodique
The FEBS journal
Auteur⸱e⸱s
Gerganova V., Martin S.G.
ISSN
1742-4658 (Electronic)
ISSN-L
1742-464X
Statut éditorial
In Press
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: aheadofprint
Résumé
Even the simplest cells show a remarkable degree of intracellular patterning. Like developing multicellular organisms, single cells break symmetry to establish polarity axes, pattern their cortex and interior, and undergo morphogenesis to acquire sometimes complex shapes. Symmetry-breaking and molecular patterns can be established through coupling of negative and positive feedback reactions in biochemical reaction-diffusion systems. Physical forces, perhaps best studied in the contraction of the metazoan acto-myosin cortex, which induces cortical and cytoplasmic flows, also serve to pattern-associated components. A less investigated physical perturbation is the in-plane flow of plasma membrane material caused by membrane trafficking. In this review, we discuss how bulk membrane flows can be generated at sites of active polarized secretion and growth, how they affect the distribution of membrane-associated proteins, and how they may be harnessed for patterning and directional movement in cells across the tree of life.
Mots-clé
cell polarity, endocytosis, exocytocis, membrane, patterning, secretion, self-organization
Pubmed
Web of science
Open Access
Oui
Création de la notice
06/12/2021 8:54
Dernière modification de la notice
01/03/2022 8:10
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