Glucosurie rénale [Renal glucosuria].

Détails

ID Serval
serval:BIB_638A96EBF30A
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Glucosurie rénale [Renal glucosuria].
Périodique
Revue Médicale Suisse
Auteur⸱e⸱s
Rohfleisch A., Nseir G., Chehade H., Noverraz M.G., Venetz J.P., Barbey F.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Statut éditorial
Publié
Date de publication
2013
Volume
9
Numéro
378
Pages
636-640
Langue
français
Notes
Publication types: Case Reports ; English Abstract ; Journal ArticlePublication Status: ppublish. PDF type: Synthèse
Résumé
The occurrence of glucosuria in the absence of hyperglycemia is distinctive for renal glucosuria. SGLT2 mutations provoke familial renal glucosuria characterized by persistent glucosuria in the absence of any other renal tubular dysfunction. Renal glucosuria associated with others proximal tubular dysfunctions points to Fanconi syndrome. This generalized dysfunction of proximal tubule needs to be treated and may progress regarding its aetiology to chronic renal failure. The development and study of models of Fanconi syndrome has recently contributed to a better knowledge of the mechanisms implicated in the tubular transport of glucose and low-molecular-weight-proteins. This article reviews these recent developments.
Mots-clé
Adult, Biological Transport, Fanconi Syndrome/diagnosis, Fanconi Syndrome/physiopathology, Female, Glucose/metabolism, Glycosuria, Renal/etiology, Glycosuria, Renal/genetics, Humans, Infant, Kidney Tubules, Proximal/metabolism, Male, Mutation, Sodium-Glucose Transporter 2/genetics
Pubmed
Création de la notice
07/07/2013 10:53
Dernière modification de la notice
20/08/2019 14:20
Données d'usage