Glucosurie rénale [Renal glucosuria].

Details

Serval ID
serval:BIB_638A96EBF30A
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Glucosurie rénale [Renal glucosuria].
Journal
Revue Médicale Suisse
Author(s)
Rohfleisch A., Nseir G., Chehade H., Noverraz M.G., Venetz J.P., Barbey F.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
2013
Volume
9
Number
378
Pages
636-640
Language
french
Notes
Publication types: Case Reports ; English Abstract ; Journal ArticlePublication Status: ppublish. PDF type: Synthèse
Abstract
The occurrence of glucosuria in the absence of hyperglycemia is distinctive for renal glucosuria. SGLT2 mutations provoke familial renal glucosuria characterized by persistent glucosuria in the absence of any other renal tubular dysfunction. Renal glucosuria associated with others proximal tubular dysfunctions points to Fanconi syndrome. This generalized dysfunction of proximal tubule needs to be treated and may progress regarding its aetiology to chronic renal failure. The development and study of models of Fanconi syndrome has recently contributed to a better knowledge of the mechanisms implicated in the tubular transport of glucose and low-molecular-weight-proteins. This article reviews these recent developments.
Keywords
Adult, Biological Transport, Fanconi Syndrome/diagnosis, Fanconi Syndrome/physiopathology, Female, Glucose/metabolism, Glycosuria, Renal/etiology, Glycosuria, Renal/genetics, Humans, Infant, Kidney Tubules, Proximal/metabolism, Male, Mutation, Sodium-Glucose Transporter 2/genetics
Pubmed
Create date
07/07/2013 10:53
Last modification date
20/08/2019 14:20
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