A gene map of the human genome
Détails
ID Serval
serval:BIB_609F704E8253
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
A gene map of the human genome
Périodique
Science
ISSN
0036-8075 (Print)
Statut éditorial
Publié
Date de publication
10/1996
Volume
274
Numéro
5287
Pages
540-6
Notes
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Review --- Old month value: Oct 25
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Review --- Old month value: Oct 25
Résumé
The human genome is thought to harbor 50,000 to 100,000 genes, of which about half have been sampled to date in the form of expressed sequence tags. An international consortium was organized to develop and map gene-based sequence tagged site markers on a set of two radiation hybrid panels and a yeast artificial chromosome library. More than 16,000 human genes have been mapped relative to a framework map that contains about 1000 polymorphic genetic markers. The gene map unifies the existing genetic and physical maps with the nucleotide and protein sequence databases in a fashion that should speed the discovery of genes underlying inherited human disease. The integrated resource is available through a site on the World Wide Web at http://www.ncbi.nlm.nih.gov/SCIENCE96/.
Mots-clé
Amino Acid Sequence
Animals
Base Sequence
Cell Line
*Chromosome Mapping
Chromosomes, Artificial, Yeast
Computer Communication Networks
DNA, Complementary/genetics
Databases, Factual
Gene Expression
Genetic Markers
*Genome, Human
*Human Genome Project
Humans
Multigene Family
RNA, Messenger/genetics
Sequence Homology, Nucleic Acid
Sequence Tagged Sites
Pubmed
Web of science
Création de la notice
25/01/2008 17:17
Dernière modification de la notice
20/08/2019 15:17