A gene map of the human genome

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Serval ID
serval:BIB_609F704E8253
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
UNIL/CHUV
Title
A gene map of the human genome
Journal
Science
Author(s)
Schuler  G. D., Boguski  M. S., Stewart  E. A., Stein  L. D., Gyapay  G., Rice  K., White  R. E., Rodriguez-Tome  P., Aggarwal  A., Bajorek  E., Bentolila  S., Birren  B. B., Butler  A., Castle  A. B., Chiannilkulchai  N., Chu  A., Clee  C., Cowles  S., Day  P. J., Dibling  T., Drouot  N., Dunham  I., Duprat  S., East  C., Edwards  C., Fan  J. B., Fang  N., Fizames  C., Garrett  C., Green  L., Hadley  D., Harris  M., Harrison  P., Brady  S., Hicks  A., Holloway  E., Hui  L., Hussain  S., Louis-Dit-Sully  C., Ma  J., MacGilvery  A., Mader  C., Maratukulam  A., Matise  T. C., McKusick  K. B., Morissette  J., Mungall  A., Muselet  D., Nusbaum  H. C., Page  D. C., Peck  A., Perkins  S., Piercy  M., Qin  F., Quackenbush  J., Ranby  S., Reif  T., Rozen  S., Sanders  C., She  X., Silva  J., Slonim  D. K., Soderlund  C., Sun  W. L., Tabar  P., Thangarajah  T., Vega-Czarny  N., Vollrath  D., Voyticky  S., Wilmer  T., Wu  X., Adams  M. D., Auffray  C., Walter  N. A., Brandon  R., Dehejia  A., Goodfellow  P. N., Houlgatte  R., Hudson, J. R., Jr. , Ide  S. E., Iorio  K. R., Lee  W. Y., Seki  N., Nagase  T., Ishikawa  K., Nomura  N., Phillips  C., Polymeropoulos  M. H., Sandusky  M., Schmitt  K., Berry  R., Swanson  K., Torres  R., Venter  J. C., Sikela  J. M., Beckmann  J. S., Weissenbach  J., Myers  R. M., Cox  D. R., James  M. R., others 
ISSN
0036-8075 (Print)
Publication state
Published
Issued date
10/1996
Volume
274
Number
5287
Pages
540-6
Notes
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Review --- Old month value: Oct 25
Abstract
The human genome is thought to harbor 50,000 to 100,000 genes, of which about half have been sampled to date in the form of expressed sequence tags. An international consortium was organized to develop and map gene-based sequence tagged site markers on a set of two radiation hybrid panels and a yeast artificial chromosome library. More than 16,000 human genes have been mapped relative to a framework map that contains about 1000 polymorphic genetic markers. The gene map unifies the existing genetic and physical maps with the nucleotide and protein sequence databases in a fashion that should speed the discovery of genes underlying inherited human disease. The integrated resource is available through a site on the World Wide Web at http://www.ncbi.nlm.nih.gov/SCIENCE96/.
Keywords
Amino Acid Sequence Animals Base Sequence Cell Line *Chromosome Mapping Chromosomes, Artificial, Yeast Computer Communication Networks DNA, Complementary/genetics Databases, Factual Gene Expression Genetic Markers *Genome, Human *Human Genome Project Humans Multigene Family RNA, Messenger/genetics Sequence Homology, Nucleic Acid Sequence Tagged Sites
OAI-PMH
oai:serval.unil.ch:BIB_609F704E8253
DOI
10.1126/science.274.5287.540
Pubmed
8849440
Web of science
A1996VN91900037
Create date
25/01/2008 17:17
Last modification date
20/08/2019 15:17
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