Atrial, ventricular or both cannulation sites to optimize left ventricular assistance?

Détails

ID Serval
serval:BIB_5FFE726B4BF2
Type
Actes de conférence (partie): contribution originale à la littérature scientifique, publiée à l'occasion de conférences scientifiques, dans un ouvrage de compte-rendu (proceedings), ou dans l'édition spéciale d'un journal reconnu (conference proceedings).
Sous-type
Abstract (résumé de présentation): article court qui reprend les éléments essentiels présentés à l'occasion d'une conférence scientifique dans un poster ou lors d'une intervention orale.
Collection
Publications
Institution
Titre
Atrial, ventricular or both cannulation sites to optimize left ventricular assistance?
Titre de la conférence
46th Annual Conference of the American Society for Artificial Internal Organ (ASAIO)
Auteur(s)
Tevaearai H., Mueller X., Jegger D., Horisberger J., von Segesser L.K.
Adresse
New York, New York, United-States, June 28-July 1, 2000
ISBN
1058-2916
Statut éditorial
Publié
Date de publication
2000
Peer-reviewed
Oui
Volume
46
Série
ASAIO Journal
Pages
173
Langue
anglais
Résumé
The efficiency of left ventricular assist devices (LVAD) depends on the capacity of the inflow cannula to drain blood into the pump. Left atrial (LA) and left ventricular (LV) sites are compared in an animal model mimicking different hemodynamic situations. Three calves (56.3±5.0 kg) monitored with ECG, arterial pressure and central venous pressure (CVP) were equipped with a Thoratec LVAD used in fill-empty mode. A regular CPB pump was used as a RVAD (jugular vein/pulmonary artery). CVP was adjusted to defined preload conditions by storage (or perfusion) of blood into (or from) the venous reservoir. We compared the LA and LV inflow cannulation sites, used separately or simultaneously, on the output of the LVAD, tested alone on a beating heart, and with the CPB (BiVAD) on a beating then fibrillating heart. In every conditions, increase of CVP highlighted the differences of LVAD's performance due to the sites of inflow cannulation. For a CVP of 14 mmHG, LVAD used on a beating heart was better with the LV (4.5±0.4 l/min) as compared to the LA cannulation (3.9±0.4 l/min, p < 0.01). Results were similar with a BiVAD used on a beating heart (4.9±0.2 1/min for LV vs. 3.8±0.6 l/min for LA cannulation, p < 0.001). However, with a fibrillating heart, LA cannulation allowed better LVAD performance (2.9±0.3 vs. 2.4±0.1 l/min, p < 0.001). Using both LV and LA inflow cannulae simultaneously, did not improve the LVAD output in none of the situations. LV cannulation increases LVAD performance in beating hearts. However, because the fibrillating heart represents the extreme of a failing heart, the use of a LA site for inflow cannulation must be considered for a better BiVAD performance.
Mots-clé
Animals, Cattle, Heart Atria, Heart Failure/physiopathology, Heart Failure/surgery, Heart Ventricles, Heart-Assist Devices, Prosthesis Implantation, Ventricular Function, Left, Ventricular Function, Right
Création de la notice
28/01/2008 9:28
Dernière modification de la notice
20/08/2019 14:17
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