Hepatitis C: molecular virology and antiviral targets

Détails

ID Serval
serval:BIB_5DD1617BC445
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Hepatitis C: molecular virology and antiviral targets
Périodique
Trends in Molecular Medicine
Auteur(s)
Moradpour  D., Brass  V., Gosert  R., Wolk  B., Blum  H. E.
ISSN
1471-4914 (Print)
Statut éditorial
Publié
Date de publication
10/2002
Volume
8
Numéro
10
Pages
476-82
Notes
Journal Article
Research Support, Non-U.S. Gov't
Review --- Old month value: Oct
Résumé
Chronic hepatitis C is a leading cause of liver cirrhosis and hepatocellular carcinoma worldwide. Although current treatment options are limited, progress in understanding the molecular virology of hepatitis C has led to the identification of novel antiviral targets. Moreover, in vitro and in vivo model systems have been developed that allow systematic evaluation of new therapeutic strategies. This review details current concepts in molecular virology and emerging therapies for hepatitis C.
Mots-clé
Animals Antiviral Agents/*therapeutic use Genes, Viral Hepacivirus/*genetics/metabolism/ultrastructure Hepatitis C/drug therapy/metabolism/*therapy/*virology Humans Models, Molecular Protein Processing, Post-Translational Protein Structure, Quaternary Viral Structural Proteins/chemistry/metabolism
Pubmed
Web of science
Création de la notice
25/01/2008 16:05
Dernière modification de la notice
20/08/2019 14:15
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