Hepatitis C: molecular virology and antiviral targets
Details
Serval ID
serval:BIB_5DD1617BC445
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Hepatitis C: molecular virology and antiviral targets
Journal
Trends in Molecular Medicine
ISSN
1471-4914 (Print)
Publication state
Published
Issued date
10/2002
Volume
8
Number
10
Pages
476-82
Notes
Journal Article
Research Support, Non-U.S. Gov't
Review --- Old month value: Oct
Research Support, Non-U.S. Gov't
Review --- Old month value: Oct
Abstract
Chronic hepatitis C is a leading cause of liver cirrhosis and hepatocellular carcinoma worldwide. Although current treatment options are limited, progress in understanding the molecular virology of hepatitis C has led to the identification of novel antiviral targets. Moreover, in vitro and in vivo model systems have been developed that allow systematic evaluation of new therapeutic strategies. This review details current concepts in molecular virology and emerging therapies for hepatitis C.
Keywords
Animals
Antiviral Agents/*therapeutic use
Genes, Viral
Hepacivirus/*genetics/metabolism/ultrastructure
Hepatitis C/drug therapy/metabolism/*therapy/*virology
Humans
Models, Molecular
Protein Processing, Post-Translational
Protein Structure, Quaternary
Viral Structural Proteins/chemistry/metabolism
Pubmed
Web of science
Create date
25/01/2008 17:05
Last modification date
20/08/2019 15:15
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