Femtosecond Laser-Assisted Intra-Corneal Drug Delivery.

Détails

ID Serval
serval:BIB_5BFB9A7082E8
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Institution
Titre
Femtosecond Laser-Assisted Intra-Corneal Drug Delivery.
Périodique
Seminars in ophthalmology
Auteur⸱e⸱s
Pallikaris I.G., Kymionis G.D., Plaka A.D., Binder P.S., Kontadakis G.A., Tsoulnaras K.I.
ISSN
1744-5205 (Electronic)
ISSN-L
0882-0538
Statut éditorial
Publié
Date de publication
2015
Peer-reviewed
Oui
Volume
30
Numéro
5-6
Pages
457-461
Langue
anglais
Notes
Publication types: Case Reports ; Journal Article
Publication Status: ppublish
Résumé
To present a case of fungal keratitis that was successfully treated with direct intrastromal medication delivery through a corneal incision created with the femtosecond laser.
A 71-year-old female patient with recurrent episodes of an unresponsive, deep stromal keratitis for six months' duration, resistant to various therapeutic approaches, was referred to our institute. The 150 kHz Intralase iFS laser (Abbott Medical Optics Inc., Santa Ana, CA) was used to create a corneal pocket in an attempt to permit drug delivery directly into the corneal abscess.
Five days after the intrastromal injections, the clinical condition was improved. Two years after the procedure, the cornea is stable and free of any clinical signs or symptoms of recurrence.
In this case report, an alternative application of femtosecond laser technology is presented, performing intrastromal drug delivery through a corneal incision for the treatment of fungal keratitis.
Mots-clé
Abscess/drug therapy, Abscess/microbiology, Abscess/pathology, Aged, Anti-Bacterial Agents/administration & dosage, Antifungal Agents/administration & dosage, Corneal Stroma/surgery, Corneal Surgery, Laser/methods, Corneal Ulcer/drug therapy, Corneal Ulcer/microbiology, Corneal Ulcer/pathology, Drug Delivery Systems, Drug Implants, Drug Therapy, Combination, Eye Infections, Fungal/drug therapy, Eye Infections, Fungal/microbiology, Eye Infections, Fungal/pathology, Female, Fluoroquinolones/administration & dosage, Humans, Lasers, Excimer/therapeutic use, Moxifloxacin, Voriconazole/administration & dosage, Corneal abscess, femtosecond laser, fungus, intracorneal drug, keratitis
Pubmed
Web of science
Création de la notice
01/10/2019 12:49
Dernière modification de la notice
06/10/2019 5:26
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