Femtosecond Laser-Assisted Intra-Corneal Drug Delivery.

Details

Serval ID
serval:BIB_5BFB9A7082E8
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Femtosecond Laser-Assisted Intra-Corneal Drug Delivery.
Journal
Seminars in ophthalmology
Author(s)
Pallikaris I.G., Kymionis G.D., Plaka A.D., Binder P.S., Kontadakis G.A., Tsoulnaras K.I.
ISSN
1744-5205 (Electronic)
ISSN-L
0882-0538
Publication state
Published
Issued date
2015
Peer-reviewed
Oui
Volume
30
Number
5-6
Pages
457-461
Language
english
Notes
Publication types: Case Reports ; Journal Article
Publication Status: ppublish
Abstract
To present a case of fungal keratitis that was successfully treated with direct intrastromal medication delivery through a corneal incision created with the femtosecond laser.
A 71-year-old female patient with recurrent episodes of an unresponsive, deep stromal keratitis for six months' duration, resistant to various therapeutic approaches, was referred to our institute. The 150 kHz Intralase iFS laser (Abbott Medical Optics Inc., Santa Ana, CA) was used to create a corneal pocket in an attempt to permit drug delivery directly into the corneal abscess.
Five days after the intrastromal injections, the clinical condition was improved. Two years after the procedure, the cornea is stable and free of any clinical signs or symptoms of recurrence.
In this case report, an alternative application of femtosecond laser technology is presented, performing intrastromal drug delivery through a corneal incision for the treatment of fungal keratitis.
Keywords
Abscess/drug therapy, Abscess/microbiology, Abscess/pathology, Aged, Anti-Bacterial Agents/administration & dosage, Antifungal Agents/administration & dosage, Corneal Stroma/surgery, Corneal Surgery, Laser/methods, Corneal Ulcer/drug therapy, Corneal Ulcer/microbiology, Corneal Ulcer/pathology, Drug Delivery Systems, Drug Implants, Drug Therapy, Combination, Eye Infections, Fungal/drug therapy, Eye Infections, Fungal/microbiology, Eye Infections, Fungal/pathology, Female, Fluoroquinolones/administration & dosage, Humans, Lasers, Excimer/therapeutic use, Moxifloxacin, Voriconazole/administration & dosage, Corneal abscess, femtosecond laser, fungus, intracorneal drug, keratitis
Pubmed
Web of science
Create date
01/10/2019 12:49
Last modification date
06/10/2019 5:26
Usage data