Plasma carnitines: reference values in an ambulatory population.

Détails

ID Serval
serval:BIB_5B2FACD40C93
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Plasma carnitines: reference values in an ambulatory population.
Périodique
European Journal of Clinical Chemistry and Clinical Biochemistry
Auteur(s)
Boulat O., Janin B., Francioli P., Bachmann C.
ISSN
0939-4974 (Print)
ISSN-L
0939-4974
Statut éditorial
Publié
Date de publication
1993
Peer-reviewed
Oui
Volume
31
Numéro
9
Pages
585-589
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
Carnitine was determined radioenzymatically in the plasma of 415 hospital employees involved in a screening programme for prevention of major cardiovascular risks. A reference population (N = 340) was extracted after excluding subjects with hypertension, diabetes mellitus or treatment for hypercholesterolaemia. This population showed a Gaussian distribution for total and free carnitine concentrations both in females and males but not for acyl carnitine or the acyl/free ratio. Females had lower total and free carnitine concentrations but a higher ratio of acyl/free carnitine than males. These differences were not detectable in older subjects (35 years for the acyl/free ratio, 45 years for total and free carnitine concentrations). Females with a body mass index > 28 had a lower acyl/free ratio than their respective controls. The differences in carnitine concentrations indicate that sex and age should be matched in patients or experimental groups and controls in studies involving carnitine plasma concentrations.
Mots-clé
Adult, Age Factors, Ambulatory Care, Body Mass Index, Cardiovascular Diseases/blood, Cardiovascular Diseases/prevention & control, Carnitine/blood, Female, Humans, Male, Middle Aged, Reference Values, Risk Factors, Sex Factors
Pubmed
Web of science
Création de la notice
05/02/2008 11:24
Dernière modification de la notice
20/08/2019 15:14
Données d'usage