Plasma carnitines: reference values in an ambulatory population.
Details
Serval ID
serval:BIB_5B2FACD40C93
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Plasma carnitines: reference values in an ambulatory population.
Journal
European Journal of Clinical Chemistry and Clinical Biochemistry
ISSN
0939-4974 (Print)
ISSN-L
0939-4974
Publication state
Published
Issued date
1993
Peer-reviewed
Oui
Volume
31
Number
9
Pages
585-589
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Abstract
Carnitine was determined radioenzymatically in the plasma of 415 hospital employees involved in a screening programme for prevention of major cardiovascular risks. A reference population (N = 340) was extracted after excluding subjects with hypertension, diabetes mellitus or treatment for hypercholesterolaemia. This population showed a Gaussian distribution for total and free carnitine concentrations both in females and males but not for acyl carnitine or the acyl/free ratio. Females had lower total and free carnitine concentrations but a higher ratio of acyl/free carnitine than males. These differences were not detectable in older subjects (35 years for the acyl/free ratio, 45 years for total and free carnitine concentrations). Females with a body mass index > 28 had a lower acyl/free ratio than their respective controls. The differences in carnitine concentrations indicate that sex and age should be matched in patients or experimental groups and controls in studies involving carnitine plasma concentrations.
Keywords
Adult, Age Factors, Ambulatory Care, Body Mass Index, Cardiovascular Diseases/blood, Cardiovascular Diseases/prevention & control, Carnitine/blood, Female, Humans, Male, Middle Aged, Reference Values, Risk Factors, Sex Factors
Pubmed
Web of science
Create date
05/02/2008 10:24
Last modification date
20/08/2019 14:14