A fatal dothiepin overdose.

Détails

ID Serval
serval:BIB_5A04814D8C41
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Titre
A fatal dothiepin overdose.
Périodique
Forensic Science International
Auteur⸱e⸱s
Cirimele V., Kintz P., Tracqui A., Mangin P.
ISSN
0379-0738[print], 0379-0738[linking]
Statut éditorial
Publié
Date de publication
1995
Volume
76
Numéro
3
Pages
205-209
Langue
anglais
Notes
Publication types: Case Reports ; Journal Article
Publication Status: ppublish
Résumé
High pressure liquid chromatography coupled to photodiode array detector and capillary gas chromatography coupled to mass spectrometry were employed to quantify dothiepin in biological fluids, tissues and hair in a death attributed to oral dothiepin (Prothiaden) ingestion. The blood concentration of dothiepin was 5.75 mg/l. Hair analysis clearly indicated a chronic antidepressant exposure, with a dothiepin concentration of 1.89 ng/mg hair. Results are discussed in the light of the existing literature.
Mots-clé
Adult, Antidepressive Agents, Tricyclic/analysis, Antidepressive Agents, Tricyclic/poisoning, Chromatography, High Pressure Liquid, Dothiepin/analysis, Dothiepin/poisoning, Fatal Outcome, Forensic Medicine/methods, Gas Chromatography-Mass Spectrometry, Hair/chemistry, Humans, Male, Poisoning/blood, Poisoning/diagnosis
Pubmed
Création de la notice
19/10/2010 16:34
Dernière modification de la notice
20/08/2019 15:13
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