Getting Nervous: An Evolutionary Overhaul for Communication.

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ID Serval
serval:BIB_562D42148454
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Getting Nervous: An Evolutionary Overhaul for Communication.
Périodique
Annual review of genetics
Auteur⸱e⸱s
Varoqueaux F., Fasshauer D.
ISSN
1545-2948 (Electronic)
ISSN-L
0066-4197
Statut éditorial
Publié
Date de publication
27/11/2017
Peer-reviewed
Oui
Volume
51
Pages
455-476
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
The evolution of a nervous system as a control system of the body's functions is a key innovation of animals. Its fundamental units are neurons, highly specialized cells dedicated to fast cell-cell communication. Neurons pass signals to other neurons, muscle cells, or gland cells at specialized junctions, the synapses, where transmitters are released from vesicles in a Ca <sup>2+</sup> -dependent fashion to activate receptors in the membrane of the target cell. Reconstructing the origins of neuronal communication out of a more simple process remains a central challenge in biology. Recent genomic comparisons have revealed that all animals, including the nerveless poriferans and placozoans, share a basic set of genes for neuronal communication. This suggests that the first animal, the Urmetazoan, was already endowed with neurosecretory cells that probably started to connect into neuronal networks soon afterward. Here, we discuss scenarios for this pivotal transition in animal evolution.
Mots-clé
CATCHR complex, Rab proteins, SNARE proteins, endosome, lysosome, regulated secretion, vesicle trafficking
Pubmed
Web of science
Création de la notice
22/11/2017 11:22
Dernière modification de la notice
13/07/2020 16:16
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