Getting Nervous: An Evolutionary Overhaul for Communication.

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Serval ID
serval:BIB_562D42148454
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Getting Nervous: An Evolutionary Overhaul for Communication.
Journal
Annual review of genetics
Author(s)
Varoqueaux F., Fasshauer D.
ISSN
1545-2948 (Electronic)
ISSN-L
0066-4197
Publication state
Published
Issued date
27/11/2017
Peer-reviewed
Oui
Volume
51
Pages
455-476
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
The evolution of a nervous system as a control system of the body's functions is a key innovation of animals. Its fundamental units are neurons, highly specialized cells dedicated to fast cell-cell communication. Neurons pass signals to other neurons, muscle cells, or gland cells at specialized junctions, the synapses, where transmitters are released from vesicles in a Ca <sup>2+</sup> -dependent fashion to activate receptors in the membrane of the target cell. Reconstructing the origins of neuronal communication out of a more simple process remains a central challenge in biology. Recent genomic comparisons have revealed that all animals, including the nerveless poriferans and placozoans, share a basic set of genes for neuronal communication. This suggests that the first animal, the Urmetazoan, was already endowed with neurosecretory cells that probably started to connect into neuronal networks soon afterward. Here, we discuss scenarios for this pivotal transition in animal evolution.
Keywords
CATCHR complex, Rab proteins, SNARE proteins, endosome, lysosome, regulated secretion, vesicle trafficking
Pubmed
Web of science
Create date
22/11/2017 12:22
Last modification date
13/07/2020 17:16
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