Stem-cell-like T cells have a specific entry gate to the tumor.

Détails

Ressource 1Télécharger: Cancer Cell Preview_edMGB_wh_v4 author copy.pdf (277.15 [Ko])
Etat: Public
Version: Author's accepted manuscript
Licence: Non spécifiée
ID Serval
serval:BIB_51451730613C
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Lettre (letter): communication adressée à l'éditeur.
Collection
Publications
Institution
Titre
Stem-cell-like T cells have a specific entry gate to the tumor.
Périodique
Cancer cell
Auteur⸱e⸱s
Held W., Luther S.A., Petrova T.V.
ISSN
1878-3686 (Electronic)
ISSN-L
1535-6108
Statut éditorial
Publié
Date de publication
14/03/2022
Peer-reviewed
Oui
Volume
40
Numéro
3
Pages
243-245
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Comment
Publication Status: ppublish
Résumé
Tumor-infiltrated T cells with stem-cell-like properties are important for determining the immunotherapy response. In this issue of Cancer Cell, Asrir and colleagues show that their entry requires specialized tumor-associated endothelial cells that resemble immature and inflamed lymph node vessels and that immunotherapy enhances the recruitment capacity of these endothelial cells.
Mots-clé
CTLA-4 Antigen, Endothelial Cells, Humans, Immunotherapy, Lymph Nodes/pathology, Lymphocytes, Neoplasms/pathology, Neoplasms/therapy, Programmed Cell Death 1 Receptor, T-Lymphocytes/pathology, Venules/pathology
Pubmed
Web of science
Open Access
Oui
Création de la notice
01/03/2022 12:38
Dernière modification de la notice
17/05/2022 6:36
Données d'usage