Infectiologie sur mesure - 1.Immunogénétique des maladies infectieuses : premiers pas [Customised infectiology - Immunogenetics]

Détails

ID Serval
serval:BIB_4C14150B4272
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Infectiologie sur mesure - 1.Immunogénétique des maladies infectieuses : premiers pas [Customised infectiology - Immunogenetics]
Périodique
Revue medicale suisse
Auteur⸱e⸱s
Neofytos D., Bibert S., Bochud P.Y.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Statut éditorial
Publié
Date de publication
10/04/2019
Peer-reviewed
Oui
Volume
15
Numéro
646
Pages
766-770
Langue
français
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
Recent discoveries in innate immunity together with improvements in the analysis of the human genome have led to the identification of factors that make certain individuals more susceptible to infections than other. We know understand why herpes simplex virus I, a virus with a minor burden in most individuals, is responsible for devastating encephalitis in children unable to detect primo-infection of neural cells. A growing number of patients are treated with immunosuppressive drugs in the field of oncology, organ transplantation and immunology. In such patients, opportunistic infections such invasive aspergillosis are clearly associated with genetic polymorphisms. Medical immune suppression represents a possible model for personalized approaches, in which infections could be prevented by individualized prophylactic strategies based on genetic testing.
Mots-clé
Aspergillosis/genetics, Aspergillosis/immunology, Aspergillosis/therapy, Child, Humans, Immunity, Innate, Immunogenetics, Immunosuppression, Opportunistic Infections/genetics, Opportunistic Infections/therapy
Pubmed
Création de la notice
15/04/2019 17:33
Dernière modification de la notice
20/08/2019 15:00
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