Multimodal Supervised Exercise Significantly Improves Walking Performances Without Changing Hemodynamic Parameters in Patients With Symptomatic Lower Extremity Peripheral Artery Disease.

Détails

ID Serval
serval:BIB_465FEECE3FBE
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Multimodal Supervised Exercise Significantly Improves Walking Performances Without Changing Hemodynamic Parameters in Patients With Symptomatic Lower Extremity Peripheral Artery Disease.
Périodique
Vascular and endovascular surgery
Auteur(s)
Calanca L., Lanzi S., Ney B., Berchtold A., Mazzolai L.
ISSN
1938-9116 (Electronic)
ISSN-L
1538-5744
Statut éditorial
Publié
Date de publication
10/2020
Peer-reviewed
Oui
Volume
54
Numéro
7
Pages
605-611
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
We evaluated the outcome of multimodal supervised exercise training (SET) on walking performances and different hemodynamic parameters (ankle/toe-brachial index [ABI/TBI], and transcutaneous oxygen pressure [TcPO <sub>2</sub> ]) in patients with symptomatic lower extremity peripheral artery disease (PAD). Whether hemodynamic parameters predict walking performances at baseline and following SET was also investigated. Fontaine stage II PAD's patients following a 3-month SET were retrospectively included. Hemodynamic parameters and walking performances (pain-free [PFWD], maximal [MWD], and 6-minute [6MWD] walking distance) were measured in each patient. Eighty-five symptomatic PAD patients were included. Following SET, PFWD, MWD, and 6MWD significantly increased (+142%, +94%, +14%; respectively; P ≤ .001). Toe-brachial index significantly increased (MD: 0.04 ± 0.01; P = .02), whereas ABI and TcPO <sub>2</sub> did not change significantly. At baseline, patients with higher TBI and TcPO <sub>2</sub> performed significantly better (PFWD: β = 0.25, P = .01 for TBI; PFWD: β = 0.30, P = .005, and MWD: β = 0.22, P = .04, for TcPO <sub>2</sub> ). No significant relationship was observed at baseline between ABI and walking performances. Baseline values of hemodynamic parameters did not significantly correlate with changes in walking performances. Multimodal SET significantly improves walking performances. Following SET, no significant changes in ABI and TcPO <sub>2</sub> were observed. Toe-brachial index values significantly improved after SET. However, this increase was very modest and its clinical relevance remains questionable. Although baseline TBI and supine TcPO <sub>2</sub> values predict baseline walking performances, no association was found between baseline hemodynamic parameters and changes in walking performances following SET.
Mots-clé
Aged, Ankle Brachial Index, Blood Gas Monitoring, Transcutaneous, Exercise Therapy/methods, Exercise Tolerance, Female, Hemodynamics, Humans, Intermittent Claudication/diagnosis, Intermittent Claudication/physiopathology, Intermittent Claudication/therapy, Lower Extremity/blood supply, Male, Middle Aged, Muscle Strength, Peripheral Arterial Disease/diagnosis, Peripheral Arterial Disease/physiopathology, Peripheral Arterial Disease/therapy, Recovery of Function, Resistance Training, Retrospective Studies, Time Factors, Treatment Outcome, Walk Test, Walking, 6-minute walking test, intermittent claudication, multimodal training, vascular rehabilitation
Pubmed
Web of science
Création de la notice
24/07/2020 12:57
Dernière modification de la notice
02/02/2021 14:47
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