Microdroplets in microfluidics: an evolving platform for discoveries in chemistry and biology.

Détails

ID Serval
serval:BIB_44866C117AE0
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Microdroplets in microfluidics: an evolving platform for discoveries in chemistry and biology.
Périodique
Angewandte Chemie
Auteur(s)
Theberge A.B., Courtois F., Schaerli Y., Fischlechner M., Abell C., Hollfelder F., Huck W.T.
ISSN
1521-3773 (Electronic)
ISSN-L
1433-7851
Statut éditorial
Publié
Date de publication
2010
Peer-reviewed
Oui
Volume
49
Numéro
34
Pages
5846-5868
Langue
anglais
Résumé
Microdroplets in microfluidics offer a great number of opportunities in chemical and biological research. They provide a compartment in which species or reactions can be isolated, they are monodisperse and therefore suitable for quantitative studies, they offer the possibility to work with extremely small volumes, single cells, or single molecules, and are suitable for high-throughput experiments. The aim of this Review is to show the importance of these features in enabling new experiments in biology and chemistry. The recent advances in device fabrication are highlighted as are the remaining technological challenges. Examples are presented to show how compartmentalization, monodispersity, single-molecule sensitivity, and high throughput have been exploited in experiments that would have been extremely difficult outside the microfluidics platform.

Mots-clé
Electrochemical Techniques, Gels/chemistry, Mass Spectrometry, Microfluidics/instrumentation, Microfluidics/methods, Polymerase Chain Reaction, Polymers/chemistry, Small Molecule Libraries/chemical synthesis, Small Molecule Libraries/chemistry, Spectrometry, Fluorescence, Spectrum Analysis, Raman, Surface-Active Agents/chemistry
Pubmed
Web of science
Création de la notice
02/02/2017 8:12
Dernière modification de la notice
20/08/2019 13:48
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