Controlling complexity: the clinical relevance of mouse complex genetics.
Détails
ID Serval
serval:BIB_419668E1C8F5
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Controlling complexity: the clinical relevance of mouse complex genetics.
Périodique
European Journal of Human Genetics
Collaborateur⸱rice⸱s
SYSGENET consortium
Contributeur⸱rice⸱s
Andreux P., Aransay AM., Auwerx J., Balling R., Banerjee S., Bezerianos A., Bragonzi AD., Brockmann GA., Brown S., Campbell-Tofte J., Cendelin J., Chatziioannou A., Chen D., Crusio W., Dimitrakopoulou K., Falcon JM., Forejt J., Franken P., Fröhlich LF., Herault Y., Hovatta I., Iraqi FA., Jansen RC., Kaczmarek L., Kas M., Knapska E., Koks S., Kolisis F., Korostynski M., Lammert F., Lehrach H., Lengeling A., Libert C., Montagutelli X., Morahan G., Mott R., Panthier JJ., Przewlocki R., Ranki A., Santos J., Severcan F., Schalkwyk L., Schughart K., Smit AB., Terasmaa A., Vasar E., Zatloukal K.
ISSN
1476-5438 (Electronic)
ISSN-L
1018-4813
Statut éditorial
Publié
Date de publication
2013
Volume
21
Numéro
11
Pages
1191-1196
Langue
anglais
Notes
h
Résumé
Experimental animal models are essential to obtain basic knowledge of the underlying biological mechanisms in human diseases. Here, we review major contributions to biomedical research and discoveries that were obtained in the mouse model by using forward genetics approaches and that provided key insights into the biology of human diseases and paved the way for the development of novel therapeutic approaches.
Mots-clé
Animals, Biomedical Research, Humans, Mice, Models, Animal, Reverse Genetics
Pubmed
Web of science
Open Access
Oui
Création de la notice
30/06/2015 8:47
Dernière modification de la notice
20/08/2019 13:42
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