Neurofibromatosis of von Recklinghausen: a quantitative study of the epidermal keratinocyte and melanocyte populations.

Détails

ID Serval
serval:BIB_4052810C1967
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Neurofibromatosis of von Recklinghausen: a quantitative study of the epidermal keratinocyte and melanocyte populations.
Périodique
Journal of Investigative Dermatology
Auteur(s)
Frenk E., Marazzi A.
ISSN
0022-202X (Print)
ISSN-L
0022-202X
Statut éditorial
Publié
Date de publication
1984
Volume
83
Numéro
1
Pages
23-25
Langue
anglais
Notes
Publication types: Comparative Study ; Journal Article
Résumé
The numerical keratinocyte to melanocyte relation was studied in café au lait spots and adjacent normally pigmented skin of 9 patients with classical neurofibromatosis. Compared to normal skin of healthy individuals, the keratinocyte:melanocyte ratio distributions obtained in neurofibromatosis indicated a shift to lower values in the biopsies of café au lait spots and normally pigmented skin. These results are evidence in favor of an impaired tissue organization of the epidermis in neurofibromatosis with regard to the keratinocyte-melanocyte interrelation.
Mots-clé
Adult, Aged, Biopsy, Cell Count, Epidermis/pathology, Humans, Keratins/biosynthesis, Melanocytes/pathology, Middle Aged, Neurofibromatosis 1/pathology
Pubmed
Web of science
Création de la notice
08/09/2011 22:48
Dernière modification de la notice
20/08/2019 13:38
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