Neurofibromatosis of von Recklinghausen: a quantitative study of the epidermal keratinocyte and melanocyte populations.

Details

Serval ID
serval:BIB_4052810C1967
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Neurofibromatosis of von Recklinghausen: a quantitative study of the epidermal keratinocyte and melanocyte populations.
Journal
Journal of Investigative Dermatology
Author(s)
Frenk E., Marazzi A.
ISSN
0022-202X (Print)
ISSN-L
0022-202X
Publication state
Published
Issued date
1984
Volume
83
Number
1
Pages
23-25
Language
english
Notes
Publication types: Comparative Study ; Journal Article
Abstract
The numerical keratinocyte to melanocyte relation was studied in café au lait spots and adjacent normally pigmented skin of 9 patients with classical neurofibromatosis. Compared to normal skin of healthy individuals, the keratinocyte:melanocyte ratio distributions obtained in neurofibromatosis indicated a shift to lower values in the biopsies of café au lait spots and normally pigmented skin. These results are evidence in favor of an impaired tissue organization of the epidermis in neurofibromatosis with regard to the keratinocyte-melanocyte interrelation.
Keywords
Adult, Aged, Biopsy, Cell Count, Epidermis/pathology, Humans, Keratins/biosynthesis, Melanocytes/pathology, Middle Aged, Neurofibromatosis 1/pathology
Pubmed
Web of science
Create date
08/09/2011 22:48
Last modification date
20/08/2019 13:38
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