Infectiologie sur mesure - 3. Transplantation de microbiote fécal : l’exemple du traitement de Clostridioides difficile [Customised infectiology - Fecal microbiota transplantation : following the Clostridioides difficile pathway]

Détails

ID Serval
serval:BIB_3FB1130D6AA1
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Infectiologie sur mesure - 3. Transplantation de microbiote fécal : l’exemple du traitement de Clostridioides difficile [Customised infectiology - Fecal microbiota transplantation : following the Clostridioides difficile pathway]
Périodique
Revue medicale suisse
Auteur⸱e⸱s
Galperine T.K., Guery B.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Statut éditorial
Publié
Date de publication
10/04/2019
Peer-reviewed
Oui
Volume
15
Numéro
646
Pages
776-779
Langue
français
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
Fecal microbiota transplantation (FMT) raised, in the recent years, a growing interest, mostly in Clostridioides difficile infections (CDI). The concept of FMT is quite simple based on the administration of fecal matter from a healthy donor to a patient with a disease related to the gut microbiota imbalance (dysbiosis). Although the theory seems straightforward, the fine mechanisms are multiple and not yet completely understood. In Switzerland, FMT is considered as a drug under the pharmacist responsibility. The only official indication for FMT is multi-recurrent CDI. For practical reasons, most of the FMT are performed with fresh stools, but development of frozen forms and capsules should considerably enhance treatment delivery. Other indications are currently investigated but not yet in the clinical routine.
Mots-clé
Clostridium Infections/therapy, Clostridium difficile, Fecal Microbiota Transplantation, Humans, Switzerland
Pubmed
Création de la notice
15/04/2019 17:32
Dernière modification de la notice
20/08/2019 14:36
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