Infectiologie sur mesure - 3. Transplantation de microbiote fécal : l’exemple du traitement de Clostridioides difficile [Customised infectiology - Fecal microbiota transplantation : following the Clostridioides difficile pathway]

Details

Serval ID
serval:BIB_3FB1130D6AA1
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Infectiologie sur mesure - 3. Transplantation de microbiote fécal : l’exemple du traitement de Clostridioides difficile [Customised infectiology - Fecal microbiota transplantation : following the Clostridioides difficile pathway]
Journal
Revue medicale suisse
Author(s)
Galperine T.K., Guery B.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
10/04/2019
Peer-reviewed
Oui
Volume
15
Number
646
Pages
776-779
Language
french
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Fecal microbiota transplantation (FMT) raised, in the recent years, a growing interest, mostly in Clostridioides difficile infections (CDI). The concept of FMT is quite simple based on the administration of fecal matter from a healthy donor to a patient with a disease related to the gut microbiota imbalance (dysbiosis). Although the theory seems straightforward, the fine mechanisms are multiple and not yet completely understood. In Switzerland, FMT is considered as a drug under the pharmacist responsibility. The only official indication for FMT is multi-recurrent CDI. For practical reasons, most of the FMT are performed with fresh stools, but development of frozen forms and capsules should considerably enhance treatment delivery. Other indications are currently investigated but not yet in the clinical routine.
Keywords
Clostridium Infections/therapy, Clostridium difficile, Fecal Microbiota Transplantation, Humans, Switzerland
Pubmed
Create date
15/04/2019 17:32
Last modification date
20/08/2019 14:36
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